Search on: POLY(ADP-RIBOSE) SYNTHASE 
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Descriptor English:   Poly(ADP-ribose) Polymerases 
Descriptor Spanish:   Poli(ADP-Ribosa) Polimerasas 
Descriptor Portuguese:   Poli(ADP-Ribose) Polimerases 
Synonyms English:   PARP Polymerase
Poly ADP Ribose Transferase
Poly ADP-Ribose Synthase
Poly(ADP-Ribose) Transferase
Poly(ADPR) Polymerase
Poly(ADPribose) Polymerase
Poly ADP Ribose Synthase
Polymerase, PARP
Synthase, Poly ADP-Ribose
ADP-Ribosyltransferase (Polymerizing)
Poly(ADP-ribose) Polymerase
Poly(ADP-Ribose) Synthase
Poly ADP Ribose Polymerase  
Tree Number:   D08.811.913.400.725.115.690
Definition English:   Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleotide (NAD) onto protein targets, thus building up a linear or branched homopolymer of repeating ADP-ribose units i.e., POLY ADENOSINE DIPHOSPHATE RIBOSE. 
Entry Combination - descr/qualif English:   Poly(ADP-ribose) Polymerases/antagonists & inhibitors use Poly(ADP-ribose) Polymerase Inhibitors
 
History Note English:   2003 (1977); use NAD NUCLEOSIDASE 1975-1976 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30405 
Unique Identifier:   D011065 

Occurrence in VHL:
 

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